Researchers have found that per- and polyfluorinated alkyl substances (PFAS) alter the expression of specific genes in brain-like cells, potentially contributing to neurotoxicity. Among six tested compounds, perfluorooctanoic acid (PFOA) caused the most significant changes, downregulating genes crucial for neuron survival and upregulating those linked to cell death.
Researchers have found that per- and polyfluorinated alkyl substances (PFAS) alter the expression of specific genes in brain-like cells, potentially contributing to neurotoxicity. Among six tested compounds, perfluorooctanoic acid (PFOA) caused the most significant changes, downregulating genes crucial for neuron survival and upregulating those linked to cell death.
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